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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

No. Football punditry is a mug’s game. Better to have the benefit of hindsight. There have been 20 previous World Cups. Of those, Brazil (five titles) and Germany (four), are regular contenders. Home advantage helps, with host nations winning the trophy six times. But next year’s festival of football is being held in Russia, which has the lowest-ranked team in the tournament.
SETTING: This house is on Modena Island, about 20 miles from downtown Savannah. According to the listing agent, the community is gated and has about 20 houses sited amid live oaks and saltwater marshes. Modena Island is a part of Skidaway Island, which has an oceanography research facility operated by the University of Georgia and a large state park.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

凭借这场胜利,金州勇士队追平了由1957-1958赛季的波士顿凯尔特人队创造的卫冕冠军赛季开局14连胜纪录。而勇士队也是成为在NBA历史上,仅有的五只以14胜0负开局的球队。接下来,他们将会作客丹佛,力争在周日将纪录继续保持下去。
上榜的商学院包括来自26个国家的商学院,其中美国有35家,英国有10家,中国有9家。中国人民大学商学院(Renmin University of China School of Business)的排名上升最快,从第43名升至第18名。法国的格勒诺布尔商学院(Grenoble Business School)排名第70名,土耳其的萨班哲大学管理商学院(Sabanci University School of Management)排名第99名,巴西的Coppead排名第100名。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 从数据看LED照明行业无限“钱景”
Open Access Perspective

Soft matter science and the COVID-19 pandemic

9.The Bling Ring

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

该学院还在国际课程体验方面排名第二。在最新的毕业生当中,逾五分之四的人有过国外实习经历,逾一半学员有过在另一个国家学习超过一个月的经历。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

It shifts your kid's weight to your shoulders and core instead of your back.
8.文盲
10.Selfie Sticks
去年电影市场的一个亮点是,共有七部高质量的国产影片在票房前10名的榜单中。其中就包括真人与动画结合的《捉妖记》、以及基于经典古代故事的3D动画电影《大圣归来》。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

单词available 联想记忆:
-
HOW MUCH: $1,975,000
这些担忧给周五开幕、为期两天的G20央行行长和财长会议投下了浓重的阴影。本周国际货币基金组织(IMF)已经警告准备下调其对今年全球增长的预测,称主要经济体需要采取更多举措来刺激增长。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

……太紧张,差点昏过去。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The line of prescriptive frames and sunglasses, named “DVF | Made for Glass,” costs upwards of $1,600. Google has already partnered with Luxottica, the eyewear conglomerate behind Ray-Ban and several high-fashion eyewear offerings such as Prada. It also hired fashion executive Ivy Ross, most recently the chief marketing officer of Art.com, to lead its Glass team.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 电商法要来了,门业老板怕了吗?
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

“尽管这两位研究人员彼此独立工作,但夏普利的基本理论和罗斯的实证调查、实验和实用的设计相结合,产生了一个蓬勃发展的研究领域,并改善了很多市场的功能,”皇家研究院说。
More than 430,000 students from 1,767 universities in 31 provinces, municipalities and autonomous regions across China were surveyed. Of the respondents, 89.2% had considered starting a business, with 18.2% reporting firm intentions to do so.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

献上节日的问候与祝福,愿你拥有一个充满生机和欢乐的新年。
戴维皮林(David Pilling)

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

到了20世纪下半叶,随着歧视逐渐减少(比如在大学入学方面),白人的正式特权地位也在渐渐丧失。但是工资的增长、社会安全网的扩大以及新的受教育机会有助于弥补他们的损失。大多数成年白人都比父母更富裕、更成功,他们相信子女们会过得更好。
“We will see a lot of headlines about [emerging market export growth] picking up in the first half of 2017,” says Bhanu Baweja, head of EM cross asset strategy at UBS, who believes EM exports will show year-on-year growth of between 8 and 13 per cent in dollar terms in the first quarter of this year, “a complete postcode away” from the negative numbers currently being reported.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

报告还显示,近四分之一的人为所有账户设置同一密码。
Just because the job market is tough doesn't mean it's impossible. "You have to work harder at the job search," Challenger said.
BABYLON (Sundance, Thursday) James Nesbitt, recently seen as the obsessed father of a long-vanished child in “The Missing,” shows up here in a very different role: as a calculating old-school police commissioner who hires an American public-relations expert (Brit Marling) to update the image of Scotland Yard. Danny Boyle (“Slumdog Millionaire”) created this satirical drama, which bears some resemblance to Armando Iannucci’s political comedy film “In the Loop.”
['striktli]

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

今年六月,谷歌宣布与时尚设计师黛安o冯o芙丝汀宝合作,携手推出新款谷歌眼镜。这个举措凸显了硅谷当下的策略:招募时尚精英,赋予可穿戴设备以时尚内涵。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

调查指出,关键的是,世界的不稳定性和冲突可能继续推动通货膨胀并影响某些城市的生活成本。
chann管道+el表名词,“人或物”→航道

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 家居消费升温 预热“金九银十”
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

China denies any wrongdoing and says it is working to tackle problems of industrial overcapacity that have become more acute as its economy has slowed.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Alfonso Cuaron and his colleagues, most notably the cinematographer Emmanuel Lubezki, the production designer Andy Nicholson and the filmmaker's co-writer, Jonas Cuaron, have made a motion picture that expands the way motion pictures will be made. Readers with an interest in technology can get a sense of their extraordinary achievements from last month's cover story of American Cinematographer, which is available online. But the emotional essence of the film is already known to anyone who has seen it, and has been swept away by it-into the outer space of silence and menace, into an inner space of deep delight.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

The seven large brick tombs were likelyconstructed for people of wealth, the researchers said.
单词addition 联想记忆:
Former Disney star-turned-wild child singer Miley Cyrus followed as the number two 'celeb gone good', according to the website. Father-to-be Channing Tatum came in third.
Others have come up with some, um, creative ways to say sayonara. When staffing firm OfficeTeam asked about 600 U.S. human resources managers to describe the weirdest ways they’ve seen or heard people resign lately, here’s what they said:

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

China saw its population grow last year, along with an improved male-female ratio and the level of education, according to a survey from the National Bureau of Statistics that was released on last Wednesday.
你是不是今年遇到过一些糟糕的面试?这项调查肯定能让你振奋起来,除非你恰好也经历过类似窘境。人力资源公司OfficeTeam要求来自北美的600名管理者描述他们在2014年见过的最令人尴尬的面试失误。以下是他们给出的答案。
她和妹妹都是通过家庭辅导接受教育的。她的妹妹也出演了《Dance Moms》。去年,以两姐妹的名字创建的时尚品牌The Maddie & Mackenzie Collection问世。
倡导“女权主义外交政策”的瑞典外交部长玛戈特·瓦尔斯特伦(Margot Wallstrom)向埃伦·巴里(Ellen Barry)敞开心扉,回忆了自己年轻时被当时的男友虐待的经历。她以前从未公开说过此事。
If you haven’t heard about this, you probably haven’t been on the Chinese Internet in the last year. This simple line was left on a World of Warcraft BBS, and somehow — some are claiming it was an online agency stunt and was helped along — managed to attract over 7.1 million views and 300,000 comments in just the first 24 hours.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

当年的荷兰金融市场固然没有今天的任何科技,但他们的很多做法都和今天的交易员一样。投资者们买入证券,有时会用买入的股票质押获得贷款。用今天的话说,他们基于保证金买入股票。贷款机构为了自身安全,会要求一个超出贷款金额一定百分比的“折幅”,质押现金或证券。如果证券价格下跌超过一定幅度,贷款机构会要求投资者交出更多资金,与“折幅”保持一致。如果投资者拿不出追加保证金,贷款机构有权将证券平仓,收回贷款额。
Don't lie about your salary. Ever. Even if your employer doesn't tell us (and most do), we'll find out eventually. I've terminated two people for doing that.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

9. The Chinese militarywill demand and receive vastly expanded investments in the form of advancedaircraft and ships.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

中国社会科学院近日发布的《中国社会心态研究报告(2016)》显示,一线城市居民生活压力较大,不过小城市也未必是宜居地。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

A·O·斯科特
“谁来支付由此产生的成本呢?”纽约合作公寓和共管公寓委员会(Council of New York Cooperatives and Condominiums)的主席马克·J·卢森堡(Marc J. Luxemburg)表示,“这会给许多楼盘带来真真切切的成本。”
All employees receive a $25 monthly credit to the DreamWorks PrintCenters at the Glendale and Redwood City campuses. Charged only for supplies, the studio is able to offer inexpensive services that range from printing photographs to creating greeting cards and personalized calendars.
10.Star Wars: Rogue One

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 家具以旧换新中标企业名单揭晓
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Asli Erdogan
SAVANNAH, GA.
Video editors likely benefited from the same factors that caused the increase in photography jobs. It stands to reason that this kind of work expands alongside the need for increasingly sophisticated and appealing website designs.
n. 隧道,地道

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Sari Davidson
The capital plans to move most of its municipal departments to the suburban district of Tongzhou in 2017, the Beijing Municipal Committee announced on Wednesday.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

But now she's using her storybook looks for good, dressing up as the character to entertain children and cheer-up cancer patients.
大众创业,万众创新
We learned that animals may make choices based on aesthetics.
An odd assortment of S&P sectors led the market higher this year, with some strange bedfellows atop the leaderboard. Even if a manager had foreseen that the healthcare sector would gain 27% this year, would they have guessed that utilities would be in the No. 2 slot, with gains of 23%? Unlikely.
本届电影节最大新闻与电影无关,而是关于鞋子。据《银幕日报》报道,上周二(5月19日),数名女性在去参加托德?海因斯(Todd Haynes)执导的《卡罗尔》(Carol)首映红毯时,因穿着装饰有莱茵石的平底鞋,而被工作人员以不符合规定为由拒之门外。报道一出,社交媒体上义愤填膺。戛纳新闻办公室仓促应对,称该报道断章取义:“这么多年来,电影节的规则都没有变过(参加电影节放映会,男士着无尾半正式晚礼服,女士穿正式礼服。)而对女性高跟鞋的跟高没有特定的要求,同样对男性的亦无特殊要求。”因此,为了确保遵守规则,男女主持会被提醒记住这些规则。好了,这下清楚了,媒体放映场没有任何着装要求:着装邋遢的记者们可穿着人字拖与运动鞋随意踏上皇宫广场(Palais)的阶梯。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

陶博宏指出,日本监管机构正在鼓励基于收费的销售模式,出台了新的受信规则和其他措施,这些举措将会增强ETF的低成本吸引力。
China's consumer price inflation decelerated to just 1.3 per cent year-on-year last month, the slowest rate since May. On a month-to-month basis inflation fell by 0.3 per cent, the first negative reading since May.
n. 紧张,拉紧,血统

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

这场比赛的糟糕表现是本赛季截止现在科比打的最差的一场,但是坦白来说,这与之前的比赛并没有太大差别。在他的第二十个NBA赛季,37岁的科比的发挥已经和他的年龄相符了。
Experts offer advice for surviving -- and thriving -- in the next year:

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 家居电商化须探“特色”之路
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

2.SpaceX demonstrates a big step towards fully reusable space craft
斗转星移关我何事?我的癖好才最重要。
这位名叫波比·博伊登的小选美冠军穿着一身黑色的连衣裤,带着鬈曲的假发,非常熟练的跳着扭臀舞,向观众们飞吻。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

在2013年的这次调查中,东京重新获得“全球最贵城市”的头衔。瑞士苏黎士由于汇率波动在去年名列榜首,但今年由于政府采取了控制汇率措施,在榜单上下滑至第七。日本大阪成为全球第二贵的城市。
Johan Pettersson被授予搞笑化学奖,以表彰其揭示了瑞典小城Andersl?v居民的头发会变绿的原因,因为这里的水中含铜量太大。
从10年和20年的时间跨度来看,地域和资产类别的多元化已经证明对投资回报和风险管理有益。不幸的是,在12个月内,不一定能看到此种战略的好处。在如今这个140字微博消息和2分钟短视频盛行的时代,投资者不能以长期的表现来判断其投资组合的成败,又有何奇怪?

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 北京市废止34件涉房屋登记文件
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

n. 预算

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Law

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 2015年硅藻泥十大品牌排行榜
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Consumers in many parts of the world have a preference for buying local which has helped boost the value of local brands.
0=不是

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

纽约的一家餐馆正在尝试制作市面上最“腐败”的披萨,这种披萨表面覆盖了黄金薄片、鹅肝和松露。
要实现有效的电子邮件营销,可不只是偶尔发一封电子文宣邮件那么简单。要想构建一套有效的电子邮件营销战略,你需要一个功能齐全的工具。MailChimp似乎是市面上最佳的此类系统,它提供了各种典雅直观的电邮广告模板、先进的分段功能和营销自动化功能。
2016年中国迅猛发展的网红经济可能会达到87亿美元
release

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

? President Obama declared a "major disaster" in New York and New Jersey. Flooding devastated the coast and more than 2.3 million lost power. The National Guard rescued hundreds from flooding in New Jersey. The governor, Chris Christie, a Republican, said the damage was "unthinkable". He praised the "outstanding" co-operation he had received from Obama.
大型企业PMI为53.1,比上月下降0.7个百分点;中型企业PMI为49.8,回落1.3个百分点,意味着进入轻度收缩。小型企业PMI为49,下降0.4个百分点,意味着收缩加剧。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 瞭望|雄安新区“新”在何处
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

那么,何种力量将决定大众明年提出的问题?这取决于你的身份(和居住地)。虽然购房者在新的一年里还将迎来高风险的竞购战,但是纽约市的偏远社区(说的就是你,大广场区[Grand Concourse])将会有大量寻求廉价住宅的潜在居民——所谓廉价,也只是针对那些令多数普通人可望而不可及的黄金地段,相对而言的。
单词charity 联想记忆:

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 多项减税新举措助力企业轻装前行
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

你是个大忙人,经常会觉得事情多得忙不过来。而Asana是一款基于云计算的项目管理软件,它能够帮你把各项工作统筹起来。(相信我,我试用过所有类似软件。)灵活性是Asana软件架构的一大特点,每个“任务”或“子任务”都可以与一个更大的“项目”和“部门”联系起来。另外,你还可以为自己或你的团队设置周期性任务,从而使你的工作生活更加轻松。因为你不必再去记住所有要做的事,大可放心让Asana安排你的生活。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

这是继2016年我国首次同步调整企业和机关事业单位退休人员的基本养老金水平后,我国再次做出同步调整。
该剧在拍摄武术场景时使用的慢动作手法赢得不少好评。
Bigcommerce does particularly well among small retailers generating $1 million to $2 million in annual revenue, although its following with those in the $20 million to $30 million range is growing quickly. Roughly 70% of its existing customer base also runs a bricks-and-mortar store. For the past year, the developer has worked hard on responsive storefront templates that work equally well on mobile platforms and desktops—design is the number-one consideration for small e-commerce merchants, it says—and on relationships with partners of “adjacent” cloud services from the accounting, payments, customer relationship management, and payroll management worlds.
然而,还有人认为医生的所作所为可能是受不公平的体制所迫。另一位网友称:“作为一个病人,我更关心他们能否治好我的病,而不是他们发表了多少论文。”

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Luckily, the singles are only half the story with Reputation. On "Dress," she's high on the rush of a new romantic thrill; on "New Year's Day," she's trying to figure out what she has after the party's over.
她解释说:“这一事件牵涉了许多方面,例如环境、能源、工作场所灾难和大国政府职能。它成为了人们焦虑情绪聚集的一个焦点。”

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

3. Your boss received your résumé from a contact of a contact。
美联储政策中任何意外举动的潜在影响,在2013年的“缩减恐慌”(taper tantrum)中表露无遗,当时,仅是美联储可能很快缩减其超宽松货币政策力度的暗示就足以引发一波全球恐慌。
Benmosche's abrasive morale-building exercise at AIG will take hold. The U.S. pay czar will give Benmosche leeway on pay. And a continuing rebound in the markets will give AIG a shot at repaying a good chunk of taxpayer money.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Wishing you all the happiness of the holiday season.
本周二,高等教育研究机构Quacquarelli Symonds(QS)公布的最新《QS世界大学学科排名》显示,中国约有88所大学的学科进入全球400强。
"Look What You Made Me Do" is one for the history books, and pop scholars will likely debate for generations whether it was a brilliant P.R. coup or not.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Vocal group: Little Big Town
越南声称来自中国的鸡肉、鲟鱼和果蔬降低了当地产品的市场价位,而他们却将严重过期的不法产品运至中国,甚至还形成了黑市。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 以量占领市场 达成家具高销售额
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The Warriors are one of the best teams in NBA history, and you can put their championship run up against any team in NBA history for the best playoff performance ever. But there's also a legitimate question of what this means for the sport. If the best or second-best player of all time stands no chance against this team, what does it mean for the sport's competitiveness? It hasn't been a problem so far, thanks to an extremely wild offseason, but the question remains: what happens to a competitive sports league when it's not truly competitive at the highest level?
以下是第68届年度黄金时段艾美奖的主要获奖者名单,请登陆emmys.com浏览获奖名单完整版。
China’s commercial banks are the control centre of the financial system and supply almost 70% of the financing that feeds the real economy.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 行业颠覆元年家居市场涌现新变化
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The app D'Aloisio designed, Summly, compresses long pieces of text into a few representative sentences. When he released an early iteration, tech observers realized that an app that could deliver brief, accurate summaries would be hugely valuable in a world where we read everything-from news stories to corporate reports-on our phones, on the go. The app attracted the interest of investors around the world, ranging from Hollywood celebrities to Hong Kong billionaire Li Ka-shing, the wealthiest man in Asia.
The World Cup, on the other hand, was searched for as both a sporting event and a cultural experience.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.
“…was checking his cell phone and chewing gum during the meeting.”
节目4 小品《我要上春晚》,周炜 刘大成 石头 张尧等

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 建筑节能催生绿色建材产品大发展
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

As China clears the way forfreer markets and increased foreign participation, fortifies the infrastructureof its burgeoning cities, and creates the social conditions for middle classfamilies to grow in size, confidence, and spending power, watch for continuedgrowth in the world’s second biggest economy in 2014 and beyond.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

华莱士对一切说“好”说了一年,然后写了这本书。这个尝试既促进了他的事业,也把他带进过邪教集会。不过,电影没说的是,华莱士曾在数不清的钓鱼网站注册。显然,一直说“好”在现实生活中可不是一帆风顺。
以下是专家提供的,明年的生存和发展建议:

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

201512/415505.shtmlBritish business schools shine in the 2015 Financial Times ranking of European institutions. Not only has London Business School (LBS) kept its crown as the best business school in Europe but three other schools in Britain have achieved the biggest rises since last year.
随着《喜羊羊与灰太狼》大电影第二部《喜羊羊与灰太狼之虎虎生威》的上映,这部空前火爆的国产动画再度成为众人关注的焦点。你知道怎么用英文介绍《喜羊羊与灰太狼》么?I

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The global battle for the living room continued in Germany with Sony announcing it 2has sold 10 million PlayStation 4s worldwide. To keep that momentum going, Sony announced a number of exclusive new titles at the show, including the action game Hellblade from developer Ninja Theory, the open world adventure game Wild from Rayman creator Michel Ancel, the shooter Alienation from Housemarque, and Q Games genre-bending The Tomorrow Children. Microsoft announced that Square Enix and Crystal Dynamics Rise of the Tomb Raider, the second game in the rebooted Lara Croft franchise, will be an Xbox exclusive in 2015. Xbox will also be getting another big sequel next year with Halo 5: Guardians.
'The book is true to the character and keeps him as fans would want him, which is as the original hard-bitten guy,' he said.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Meghan Markle
(美联社)波多黎各,圣胡安市 - 波多黎各新总督周一宣誓就职,作为美国领土许多人认为要为新的紧缩措施做准备,并为该岛摆脱严重的经济危机重新推动建州或独立。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

报告称,毕业生期望就业的三大行业依次为IT/互联网/通讯/电子、金融/银行/投资/基金/证券/保险、政府/公共事业/非盈利机构。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

喜剧类最佳女演员: 茱莉亚?路易斯-德瑞弗斯(Julia Louis-Dreyfus),《副总统》(Veep)
Rare pictures have been released showing the ancient sex toys that once belonged to the Chinese royals and aristocrats.
我判断摆烂不是看言论而是看球队动作的。所以,即使球队说他们没有摆烂,但是签了一大批落选的自由球员,同时报告明星球员伤病缠身,这时候你就知道,他们是在摆烂了。
和许多评论家一样,我一方面了解清单的便利,一方面也讨厌清单的专横。所以我永远不可能只列出十部――我怎么做得到呢,北美影院一年就要上映900多部影片呢――今年是2015年,所以我挑选了15部,为它们分门别类,计数时做了一点含糊,所以最后其实是20部。其中有两部片名的不代表并列,而是代表有两种特色,可以成对观看,二者的优点相映成趣。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

海莉·威廉姆斯依然是颇有影响力的重要存在,一位不论是低声哼唱还是大声呐喊都能令人信服的歌手。她直言不讳的勇气几乎使你忘记《欢笑过后》记录的是她对这个世界的厌倦。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

调查指出,关键的是,世界的不稳定性和冲突可能继续推动通货膨胀并影响某些城市的生活成本。
Asli Erdogan, a novelist of the “dark, pessimistic,” is struggling to process her own grim experience: months in prison.
今年的最佳流行音乐专辑出自几位有许多话要讲的女强人:洛德对孤独的深刻思考,凯莎有关解放的强烈表态;泰勒·斯威夫特就真实的自己与媒体中所呈现的个人形象而与他们算总账。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

At the end of a politically charged ceremony in which Donald Trump was the subject of frequent jokes by host Jimmy Kimmel, Warren Beatty and Faye Dunaway announced that La La Land had won. But as the producers and cast of Damien Chazelle’s modern musical were on stage giving emotional thank you speeches, they were told that Moonlight was the real winner.
3. Your boss received your résumé from a contact of a contact。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Steven Spielberg directs Meryl Streep and Tom Hanks in The Post, a thrilling drama about the unlikely partnership between The Washington Post's Katharine Graham (Streep), the first female publisher of a major American newspaper, and editor Ben Bradlee (Hanks), as they race to catch up with The New York Times to expose a massive cover-up of government secrets that spanned three decades and four U.S. Presidents. The two must overcome their differences as they risk their careers - and their very freedom - to help bring long-buried truths to light.
James Franco’s new movie about the making of The Room will make you belly-laugh, but its comedy is also deeper and richer than mere mockery.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 抢人才,名企承诺可“分房”
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

The December budget deal was hardly the kind of confidence-boosting agreement Washington has been debating for years. But at least it hit the pause button on the serial brinkmanship that threatened to derail the recovery each of the past three years.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

If the user set up a truthful answer, according to statistics provided by the researchers, in 19.7% of the cases, an attacker would need a single try to guess the correct answer to the question "What is your favorite food?" in the case of American users.
For the government, the job is to create a good environment and the necessary conditions for our people to use their own wisdom and hard work to generate golden opportunities for themselves, rather than just relying on the government to hand them a job.
Plenty of technology companies are angling for a piece of the action, from established players such eBay’s Magento , IBM , and NetSuite to smaller developers including Shopify and Volusion. But relative underdog Bigcommerce is stealing mindshare and market share, fueled by more than $75 million in venture capital, including $40 million from entrepreneur Steve Case’s Revolution Growth firm.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 陶瓷企业“跳楼价”拼抢市场
Paper

Length-scale dependence of protein hydration-shell density

"At a time when the world seems defined by division, storytellers bring us together as one," AFI president and CEO Bob Gazzale said Thursday in a statement. "AFI Awards is honored to celebrate this community of artists who challenge and inspire us, entertain and enlighten us - ultimately reminding us of our common heartbeat."
单词qualified 联想记忆:
2014年,世界杯在1978年以后又重新回到南美的怀抱,当时,马里奥·肯佩斯(Mario Kempes)带领阿根廷队战胜了荷兰队,保持着南美球队在南美洲大陆上举行的世界杯中赢得冠军的记录。那么,2014年会有所不同吗?包括卫冕冠军西班牙队在内的欧洲诸强能够实现那些在过去的比赛中的欧洲球队未能做到的吗?抑或,有其他任何大陆能够有实力挑战强大的南美球队吗?
12. 最有希望的迹象。有段时间,你会觉得现状已经改善了,人们可以公开大声谈及业内的歧视现象。维奥拉·戴维斯(Viola Davis)出来说话,詹妮弗·劳伦斯(Jennifer Lawrence)公开谈起,自己比片中的合作男星片酬少。“我不想被视为‘难搞’或者‘被宠坏了’,”她在简报《伦尼》(Lenny)中为许多人发言,其中包括许多薪酬更低的人们。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

The circular also stressed zero tolerance for cheating.
Other notable custom course performances include Harvard Business School, which recorded one of the year’s biggest rises, jumping nine places to fifth. The Massachusetts school was ranked 18th two years ago.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 家装6大霸王条款缘何被叫停?
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Institutions may also fail.
Wang Ki-young, a director at South Korea’s culture ministry, said on Friday that Chinese authorities had ordered tourism agencies in Beijing to halt tours to South Korea from mid-March. Mr Wang said the move would be expanded to other provinces.
In a working paper published on Tuesday, Robin Koepke, economist at the Institute of International Finance, an industry group, argues that investors, EM policymakers and the Fed itself have neglected the role of US interest rates in provoking currency, banking and debt crises in the emerging world.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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警方周四表示,关于14岁少女Lecent Ross的枪击案,已逮捕两人。
梅瑟威一场拳赛的要价可以高达7000万英镑,但是他去年的收入只排在榜单上位居第16位。去年梅瑟威的拳赛收入达到了2000万英镑,此外他的服装品牌TMT(The Money Team)也给他贡献了500万英镑。

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